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Posted July 11th, 2011 in Exits IPOs M&As, VC-backed Biotech Returns

Note to Readers: This blog post was co-written by Bruce Booth and Bijan Salehizadehwho co-authored an article in the July 2011 issue of Nature Biotechnologydetailing the differences in returns between Life Sciences and Tech investing.

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Left behind by this good news is the Nike M2k Tekno black de Hombre whiteo blue red Zapatillas Reino Unido Tamaño, which according to PWCMoneyTree / NVCA data accounted for nearly 30% of the $21 billion invested in venture-backed companies in 2010.

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As we outline in our paper in the July issue of Nature Biotechnology, LS venture investing dramatically outperformed Tech venture investing over the past decade.

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Overall Life Sciences/Healthcare venture realized gross pooled mean IRR was 15.0% for the past decade.  This is in contrast to 5.5% for all of venture capital, 3.0% for IT and 4.1% for Software.Nike Air Pegasus 83 30 Wolf Grey Neutral Grey bluee White-599482-014 Mens SZ 10.5,.


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There’s a perception that lots of Life Sciences deals lose money.  It’s true.  58% returned less than their invested capital.Nike Lebron Soldier XII SFG Mens AO4054-800 Lava Grey Black Volt shoes Size 9.5,.  Furthermore, the frequency of 5x or greater returns are higher in Life Sciences – 8% vs. 4% for IT.Nike Air Jordan 13 XIII Retro Grey Toe White Black Cement Grey Size 8 7.5 10,.g.,. top 1% of Tech deals almost certainly have higher multiples than LS).

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But, as one would expect, not all of the news for Life Sciences is rosy:

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Nike Lunarglide 9 X-Plore Mens 904745-001 Black Bronze Running shoes Size 9,..  And, post-IPO performance has been dramatically better in IT than it has been in Life Sciences.Jordan Retro 10 Lady Liberty sz 9.5. Deadstock Sac Galaxy Yeezy,.

NIKE KOBE XI 11 ELITE FLYKNIT LOW ID BLACK-blueE-GREEN SZ 11.5 [885003-994],.  IPOs are media darlings, and help create buzz about sectors.  In LS, we aren’t likely to have that type of buzz anytime soon.

Our data and analysis of course has some short-comings.MEN NIKE LEBRON JAMES XII BASKETBALL SHOE SIZE 10.5 EASTER,.  However, it has been shown by others that the recent web high flyers are mostly concentratedVTG Rare Nike Air Max 95 360 Diamond Pack Safari 315859 001 Africa SZ 10.5 2007,.

Some of you who follow venture returns data may be asking some questions:

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  3. Nike LeBron XV Low Supernova Multicolor University Red AO1755-900 Men's Size 14,–  Unlike IT where 100x returns are possible and have driven great outcomes in companies like Skype and Google, and will most likely in Zynga and Facebook, Life Sciences never will have these wild “Black Swan” outliers.. These 100x’ers are the companies that draw press attention, new talent, and more capital into the IT space.
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To get all of the numbers and the full commentary, please head over to the Nature website.

For simplicity’s sake, in this post, we use the term Life Sciences to cover all of Healthcare venture capital investing and the term IT/Tech to cover all Information technology, Internet/Software, and Hardware related categories.

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